We aim at an early and precise diagnosis of the disease by the detection of multiple-target biomarkers through improved sampling strategy for mass spectrometry analysis. Cancer is one of the main diseases causing death worldwide. Still the most effective treatment against cancer is early diagnosis, as cancer is very heterogeneous regarding its cause, and different proteins are correlated to its metabolism. A new method for multi-biomarker detection is urgently required for monitoring or prediction of the progression of the disease. The aim is to implement grafting multi-aptamers onto ISET-MS which is cutting-edge intersectional research and a challenge from a technological perspective.
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