Tissue engineering aims at building functional tissues that can repair damaged tissues and organs. Most healthy organs and tissues come from a deceased donor that must be compatible with the ill patient. Critical patients do not survive the waiting time. Only in Sweden, 700 organ and 1000 tissue transplantations are necessary yearly. A simple and effective method to remove cells and lipids from donor organs and tissue will decrease rejection of transplant and make a positive impact in life expectancy of critical patients and life quality of transplanted individuals. It may also be the key to a safe animal-to-human transplantation, solving the problem of donor shortage.